THE IMPACT OF RADIOTHERAPY ON TREATING INOPERABLE BONE SOLITARY PLASMACYTOMA :CASE REPORT

Andrianto, Yuki and Surjoseto, Robertus and Didiet, Putu B and Maryastuti, Maryastuti and Huswatun, Aida Lutfi (2023) THE IMPACT OF RADIOTHERAPY ON TREATING INOPERABLE BONE SOLITARY PLASMACYTOMA :CASE REPORT. In: 18th Annual Meeting of Asian Society for Neuro-Oncology (ASN), 25-29 Oktober 2023, Bali.

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Abstract

Objective A bone solitary plasmacytoma is a rare disorder, a mass of abnormal plasma cells in bone and soft tissue. Radiotherapy may be the most effective treatment option for inoperable tumors. Case A 67-year-old female reported back pain since the end of 2022, with no history of previous injuries. Months 25 - 26 & 27-29 October 2023 Hyatt Regency Hotel │ Sanur, Bali - Indonesia E-POSTER ABSTRACT 69 later, she couldn't flex both of her legs and walking was excruciatingly painful. On January 2023, an MRI vertebra result revealed a paravertebral mass at vertebral bodies of lumbar 2 - 4, resulting in the destruction of vertebral bodies of lumbar 2, stenosis of the spinal canal, and compression of the cauda equina. On February 2023, the patient underwent a core biopsy due to the high risk of operation due to age. She could flex her legs after surgery, but she still had back pain and couldn't walk. A biopsy revealed plasmacytoma. Because of her age, the patient was recommended to radiotherapy. The patient underwent CT simulation with a pelvic mask to minimize mobility. MRI and simulation images were compared. Gross tumor volume (GTV) was used to define the lesion. CTV was characterized as a 1 cm margin expansion from GTV. PTV was defined as a 0.7 cm margin expansion from CTV. Intensity modulated radiation treatment (IMRT) with 40 Gy in 20 fractions is planned. The generated plans were compared for dosage distributions of GTV, CTV, PTV, and different nearby organs at risk (OARs), including both kidneys, bowel, liver, and spinal cord. After 5 weeks of radiotherapy, there were no side effects and could flex both knees and get up, despite slight pain. Conclusion In the treatment of unresectable Solitary Bone Plasmacytoma, radiotherapy is an effective treatment. A radiation dose of 40 Gy appears to be a successful treatment for mass control and patient improvement with few side effects. ___________________________________________________________________________________________

Item Type: Conference or Workshop Item (Poster)
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicine and Health > Profession of Doctor / Profesi Dokter
Depositing User: Mr ROBERTUS SURJOSETO
Date Deposited: 24 Jan 2024 06:52
Last Modified: 24 Jan 2024 06:52
URI: http://repository.umj.ac.id/id/eprint/17624

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