Extraction and Formulation of Quersetin Nanoemulation from Kenikir Leaves (Cosmos Caudatus Kunt) in the Phase of RBO Oil as Antioxidant

Nugrahani, Ratri Ariatmi and Fithriyah, Nurul Hidayati and Ismiyati, Ismiyati Extraction and Formulation of Quersetin Nanoemulation from Kenikir Leaves (Cosmos Caudatus Kunt) in the Phase of RBO Oil as Antioxidant. turnitin.

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Abstract

This study was an effort to obtain high yield of quercetin extraction from kenikir leaves employing several extraction methods, which were maceration, percolation, soxhlet, and reflux, using methanol as solvent followed by quercetin incorporation into a Nanoemulsion system with Rice bran oil (RBO) as the oil phase. The resulting Nanoemulsion was tested with antioxidant activity analyses using DPPH (1,1-diphenyl-2-picrylhydrazil) reagent. The nanoemulsion preparation was produced from kenikir leaf powder at 20% concentration. The characterizations of formula consisted of organoleptic tests, analyses of pH, particle size, emulsion type, and determination of quercetin content absorbed in the nanoemulsion system, as well as antioxidant activity testing. The results showed that the highest quercetin yield of 14.26 ppm was produced from the soxhlet method for two hours. The Nanoemulsion preparation with 20% kenikir leaf extract and RBO oil phase was good and stable. The formulations also exhibited 6.3 pH, O/W emulsion type, and 176.8 nm particle size. The absorption of quercetin in the nanoemulsion showed an %EE value of 99.99%, indicating the formulation’s high capacity to absorb quercetin. The antioxidant activity testing using DPPH assay produced an IC50 value of 106.805 ppm.

Item Type: Other
Subjects: T Technology > TP Chemical technology
Divisions: Faculty of Engineering / Fakultas Teknik > S1 Chemical Engineering / Teknik Kimia
Depositing User: Dr Ir Ratri Ariatmi Nugrahani
Date Deposited: 04 Apr 2023 03:02
Last Modified: 04 Apr 2023 03:02
URI: http://repository.umj.ac.id/id/eprint/12854

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